Table 1.
Patient and sample characteristics.
| Variables | |
|---|---|
| No. of patients | 109 |
| Patient age, mean (range) | 26 (6–57) |
| Male, count (%) | 57 (52) |
| No. of samples | 818 |
| No. of samples per patient, mean (range) | 8 (1–29) |
| Sampling frequency, mean days (range) | 97 (3–741) |
| Sequencing runs | 14 |
| No. of samples per run, mean (range) | 58 (27–88) |
| CFTR genotype, count (%) | |
| F508del homozygous | 51 (47) |
| F508del heterozygous | 42 (39) |
| Others | 9 (8) |
| Unidentified | 7 (6) |
| Disease aggressiveness, count (%) | |
| Mild | 42 (38) |
| Moderate | 41 (38) |
| Severe | 26 (24) |
| Clinical statea, count (%) | |
| Baseline | 254 (31) |
| Exacerbation | 150 (18) |
| Treatment | 219 (27) |
| Recovery | 134 (17) |
| Unknown | 61 (7) |
| Disease stagea, count (%) | |
| Early | 178 (22) |
| Intermediate | 254 (31) |
| Advanced | 154 (19) |
| Unknown | 232 (28) |
aPatient clinical state and disease stage at the time of sample collection.