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. 2022 Mar 22;12:4836. doi: 10.1038/s41598-022-08895-6

Table 5.

Univariate and multivariate analysis of factors associated with parents’ positive attitude on appropriate use of antibiotic in children.

Variable Categories Univariate analysis Multivariate analysis
cOR 95% CI P-value aOR 95% CI P-value
Parents’ age (years) > 45 1.08 0.76–1.54 0.677 1.19 0.79–1.77 0.405
36–45 1.35 1.08–1.68 0.007 1.16 0.91–1.49 0.234
25–35 1.33 1.10–1.60 0.003 1.10 0.90–1.35 0.357
< 25 Ref Ref
Number of children ≥ 3 1.07 0.90–1.28 0.447
2 1.20 0.99–1.46 0.063
1 Ref
Parents’ sex Female 0.81 0.68–0.98 0.029 0.76 0.62–0.94 0.010
Male Ref Ref
Marital status Married 1.28 1.06–1.54 0.010 1.03 0.77–1.38 0.844
Not married Ref Ref
Occupation Employed 1.93 1.58–2.36  < 0.001 1.20 0.94–1.55 0.148
Self-employed 1.19 1.01–1.40 0.040 0.96 0.80–1.15 0.634
Not employed Ref Ref
Education level Degree/masters 8.79 5.60–13.82  < 0.001 5.30 3.24–8.65  < 0.001
Diploma 2.54 1.66–3.89  < 0.001 1.38 0.85–2.23 0.187
Certificate 4.92 3.15–7.70  < 0.001 2.89 1.77–4.70  < 0.001
Advanced secondary 1.16 0.79–1.71 0.441 0.76 0.49–1.17 0.214
Primary/secondary 2.73 2.06–3.60  < 0.001 1.92 1.42–2.60  < 0.001
Literate 1.32 0.95–1.84 0.097 0.92 0.65–1.32 0.661
Illiterate Ref Ref
Family type Nuclear family 1.22 1.004–1.48 0.046 1.08 0.87–1.33 0.493
Single parent family 0.81 0.64–1.04 0.093 0.81 0.59–1.13 0.224
Extended family Ref Ref
Residence Urban 2.37 2.00–2.81  < 0.001 2.07 1.72–2.49  < 0.001
Rural Ref Ref

cOR crude odds ratio, aOR adjusted odds ratio, 95%CI 95% confidence interval, Ref reference category.