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. 2022 Mar 22;12:4344. doi: 10.1038/s41598-022-08583-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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HE and Masson trichrome straining in ischemic myocardium after cell transplantation. HE staining (A) and Masson trichrome staining (B) in sections of ischemic myocardium 30 days after treatment in each group (PBS group (a), CPC group (b), MITO-cell group (c)). Left panels are magnified images of interest of region. Scale bar is 200 μm. (C) The photographic images shown in (B) were analyzed to determine the rate of fibrosis using Image-pro Plus 7.0. PBS, PBS treated; CPC, CPC transplanted; MITO cell, MITO cell transplanted. Data are represented as the mean ± S.D (n = 5). Significant differences (**p < 0.01) were calculated by one-way ANOVA, followed by the SNK test.