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VHH–RTA binding data and interface information
| VHH | Kda | EC50a | H-bondsb |
SBc | SCd | Total BSAe | |
|---|---|---|---|---|---|---|---|
| Total | CDR1/2/3 | ||||||
| V9B2 | <0.03 | 43.0 | 2 | 1/0/1 | 5 | 0.72 | 1897 |
| V9F9 | <0.03 | 19.1 | 5 | 1/3/1 | 7 | 0.70 (0.73f) | 2028 (1994f) |
| V9E1 | 0.11 | 4.0 | 9 | 0/1/5 | 6 | 0.61 | 1864 |
| V9F6 | 0.22 | 1.9 | 11 | 5/2/4 | 0 | 0.73 | 1130 |
Nanometer, determined in in vitro translation assay.
Hydrogen bonds.
Salt bridges.
Shape complementarity.
Buried surface area.
Second VHH–RTA complex in crystallographic asymmetric unit.
