Table 4.
Enrichment of tissue-specific proteins in EVs separated from plasma and serum
| Source (tissue) | Tissue enrichmenta | Total | Plasma and Serum EVs | Plasma EVs | Serum EVs |
|---|---|---|---|---|---|
| Testis | 950 | 23 | 14 | 21 | 16 |
| Brain | 488 | 39 | 31 | 34 | 36 |
| Liver | 242 | 123 | 109 | 120 | 112 |
| Lymphoid | 123 | 13 | 13 | 13 | 13 |
| Intestine | 122 | 15 | 11 | 14 | 12 |
| Skin | 113 | 11 | 11 | 11 | 11 |
| Skeletal muscle | 111 | 19 | 16 | 18 | 17 |
| Placenta | 91 | 11 | 10 | 11 | 10 |
| Retina | 87 | 4 | 3 | 4 | 3 |
| Pancreas | 64 | 2 | 2 | 2 | 2 |
| Blood | 57 | 14 | 13 | 13 | 14 |
| Kidney | 53 | 4 | 4 | 4 | 4 |
| Salivary gland | 42 | 6 | 2 | 5 | 3 |
| Bone marrow | 29 | 15 | 13 | 15 | 13 |
| Heart muscle | 29 | 3 | 3 | 3 | 3 |
| Parathyroid | 22 | 6 | 5 | 5 | 6 |
| Breast | 19 | 2 | 1 | 2 | 1 |
| Lung | 13 | 2 | 1 | 2 | 1 |
| Thyroid gland | 13 | 1 | 1 | 1 | 1 |
| Tongue | 11 | 3 | 2 | 3 | 2 |
| Adrenal | 9 | 1 | 1 | 1 | 1 |
| Fallopian tube | 6 | 1 | 1 | 1 | 1 |
| Vagina | 3 | 2 | 2 | 2 | 2 |
a
The number of genes with enriched expression in a particular tissue compared with other tissues.