Figure 1.

Physico-chemical and structural properties

(A–C) (A) FTIR spectra of selected pure 3% HCS (), 3% LCS (), 1% HHA (), 3% HCS-1% HHA (), 4% HCS-1% HHA (), 3% HCS-2% HHA (), 3% HCS-2% HHA-1% Coll (), 3% HCS-2% HHA-2% Coll () hybrid hydrogels, and pure Coll (). Surface topographical composition acquired by Raman confocal imaging of (B) 2D projections of 3% HCS-1% HHA (left) and 3% HCS-2% HHA (right) hybrid hydrogels; (C) 3D projections of 3% HCS-1% HHA-1% Coll (left) and 3% HCS-1% HHA-2% Coll (right) hybrid ones. HHA (in red) was detected using bands at ca. 795 and 945 cm⁻¹, HCS (in blue) using that of ca. 1540–1590 cm⁻¹, and Coll that of ca. 1648 cm⁻¹, respectively.