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. 2022 Jan 25;39(1):30–38. doi: 10.5152/balkanmedj.2021.21068

Figure 1.

Figure 1

a-f. KDM5C expression was up-regulated in DLBC cell lines and down-regulation of KDM5C inhibited proliferation of OCI-Ly7 cells. (a/b) KDM5C mRNA expression and protein expression in DLBCL cells and GM12878 cells were, respectively, detected by RT-qPCR and Western blot. (c/d) KDM5C mRNA expression and protein expression in OCI-Ly7 cells transfected with shRNA-KDM5C#1/2 were, respectively, confirmed by RT-qPCR and Western blot. *P < .05, **P < .01 and ***P < .001. (e) The viability of OCI-Ly7 cells transfected with shRNA-KDM5C was analyzed by CCK-8 assay. *P < .05 and ***P < .001 vs. control group. ##P < .01 and ###P < .001 vs. shRNA-NC group. (f) The proliferation of OCI-Ly7 cells transfected with shRNA-KDM5C was analyzed by EdU staining. N = 3.