Table 1 –

Summary of cohort characteristics and task performance. Eleven subjects demonstrated faster mean reaction times (RT) in the externally cued (EC) relative to the internally cued (IC) condition. This difference was statistically significant in 5 subjects using two sample t-tests. At the group level, RT was significantly faster in the EC condition relative to the IC condition using paired t-test.

Subject	Gender	Age	UPDRS-III Off	H & Y Stage	Dominant Hand	Dominant vs Test Hand Congruence	EC Trial Count, n	EC RT, seconds, mean	IC Trial Count, n	IC RT, seconds, mean	EC vs IC RT, t-test, P-Val
1	F	57	14	2	R	No	25	0.52	24	0.61	0.01
2	M	71	21	2.5	R	Yes	49	0.51	50	0.62	<0.01
3	M	68	32	2.5	L	Yes	25	0.59	22	0.63	0.23
4	F	52	25	2	R	No	44	0.55	48	0.59	0.15
5	M	57	22	3	R	No	25	0.78	23	0.82	0.37
6	M	59	28	1.5	R	Yes	52	0.67	51	0.72	0.11
7	M	57	29	2	R	Yes	51	0.49	50	0.48	0.80
8	F	60	49	2	R	No	50	0.74	49	0.74	0.93
9	F	61	44	3	R	No	18	0.88	17	1.13	0.01
10	M	67	NA	2	R	Yes	30	0.85	24	0.89	0.34
11	F	56	35	2	L	No	51	0.61	47	0.67	0.04
12	M	68	18	2	R	No	48	0.87	45	0.95	0.02
13	M	74	21	3	L	Yes	33	0.96	43	1.02	0.26
All Subjects, mean (SD)	-	62.0 (6.7)	28.1 (10.5)	2.3 (0.50)			38.5 (12.7)	0.69 (0.16)	37.9 (13.4)	0.76 (0.19)	<0.01

EC, externally cued; H & Y, Hoehn and yahr Stage; IC, internally cued; L, left; n, number; NA, not available; RT, reaction time; UPDRS III Off, Part III of the Unified Parkinson’s Disease Rating Scale off-medications;

^*P <0.05, t-test