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. 2022 Mar 22;5(3):e223236. doi: 10.1001/jamanetworkopen.2022.3236

Table. Characteristics of Included Studies.

Source Study design Population Music intervention Music intervention group Control group
Type Length Session frequency Session duration Total, No. Men/women Mean age, y Type Total, No.
Altena et al,35 2009 RCT Clinical (hypertension) Music listening (“slow music”) 9 wk Daily Not specified 15 8/7 59 Exercises with breathing device 15
Ashok, Shanmugam, and Soman,31 2019 RCT Clinical (coronary bypass) Music listening (sedative music without lyrics with tempo 60-80 beats per minute) + TAU 1 wk Daily 20 min 20 6/14 60.8 TAU (cardiac rehabilitation) 20
Atiwannapat et al,39 2016 RCT Clinical (major depressive disorder) Music therapy (individual, active) 12 wk Weekly 1 h 5 1/4 41.6 Group counselling 4
Music therapy (individual, receptive) 12 wk Weekly 1 h 5 2/3 54.4 Group counselling 4
Bittman et al,46 2020 RCT Clinical (2 or more metabolic risk factors) Gospel music program (singing and playing musical instruments [clavinovas, guitars, drums]) + health education 1 y Weekly 45 min 36 6/30 62.5 Health education (cardiovascular risk reduction) 35
Burrai et al,32 2020 RCT Clinical (heart failure) Music listening (recorded classical music; experimenter-selected tracks with tempo 60-80 beats per minute) 12 wk Daily 30 min 82 47/35 71.6 TAU (heart failure) 77
Corvo, Skingley, and Clift,33 2020 Single group study Healthy (older people) Singing (1 singing group 12 wk Weekly 2 h 41 “Predominantly female” No data NA NA
Coulton et al,41 2015 RCT Healthy (older people) Singing (group) 14 wk Weekly 1.5 h 131 25/106 69.2 Wait list 127
Davidson et al,25 2014 Single group study Healthy (older people) Singing (group) 8 wk Weekly 1.5 h 29 21/8 77.5 NA NA
Gale et al,42 2012 Single group study Clinical (cancer survivors) Singing (group) 12 wk Weekly 2 h 30 Unspecified 60.2 NA NA
Groener et al,30 2015 RCT Clinical (diabetes) Singing (group) + Health education 3 d Daily 30 min 18 14/4 46 Health education 17
Hagemann, Martin, and Neme,26 2020 Single group study Clinical (chronic kidney disease) Music therapy (group, active) 4 wk Twice weekly 1.25 h 23 12/11 54.9 NA NA
Innes et al,47 2018 RCT Clinical (knee osteoarthritis) Music listening (recorded classical music; patient choice of 80 experimenter-selected songs) 8 wk Twice daily 20 min 11 5/6 58.8 Meditation (Mantra) 11
Innes et al,48 2016 RCT Clinical (cognitive decline) Music listening (recorded classical music; patient choice of 80 experimenter-selected songs) 12 wk Daily 12 min 30 5/25 60.2 Meditation (Kirtan Kriya) 30
Lavretsky et al,49 2013 RCT Clinical (dementia caregivers with depressive symptoms) Music listening (recorded music; experimenter provided CD) 8 wk Daily 12 min 16 2/14 60.6 Meditation (Kirtan Kriya) 23
Lee, Chan, Mok29 2010 RCT Healthy (older people) Music listening (Patient choice of experimenter-selected music; meditative, Asian classical, Western classical, slow jazz, Chinese classical) 4 wk Weekly 30 min 31 11/20 75.5 Inactive 35
Logtenberg et al,36 2007 RCT Clinical (type 2 diabetes + hypertension) Music listening (“various kinds of random music”) 8 wk Daily Not specified 15 3/12 62.7 Exercises with breathing device 15
Lord et al,45 2010 RCT Clinical (COPD) Singing (group) + breathing education 6 wk Twice weekly 1 h 15 No data 66.6 Breathing education alone 13
Lord et al,43 2012 RCT Clinical (COPD) Singing (group) + breathing education 8 wk Twice weekly 1 h 13 No data 68.6 Film workshops + breathing education 11
Mandel et al,50 2007 RCT Clinical (cardiac rehabilitation) Music therapy (active, individual) + TAU 10 wk Every other week 1.5 h 55 27/28 65 TAU (cardiac rehabilitation) 48
Mateu et al,37 2018 Single group crossover study Clinical (low-back pain) Music listening (relaxing music; patient choice of songs from provided CD) 8 wk Daily Not specified 58 15/43 51 Progressive muscle relaxation with ‘low-level background music’ 58
Mujdeci et al,40 2015 Single group study Clinical (tinnitus) Music therapy (receptive; listening to patient preferred recorded music, edited to be 70% music and 30% noise) 8 wk Daily 2 h 13 7/6 46.8 NA NA
Philip et al,44 2020 RCT Clinical (COPD) Singing (group) + TAU 12 wk Weekly 1 h 9 6/3 72.1 TAU (COPD) 9
Ribeiro,27 2018 RCT Clinical (NICU mothers) Music therapy (individual; receptive) + TAU 7 wk Weekly 45 min 10 0/10 25.8 TAU (NICU) 11
Wahlstöm et al,38 2020 RCT Clinical (atrial fibrillation) Music listening (relaxing recorded music (MediCure) delivered in group setting) + TAU 12 wk Weekly 30 min 29 14/15 64 TAU (atrial fibrillation) 41
Zanini et al,28 2009 RCT Clinical (hypertension) Music therapy (group, active) + TAU 12 wk Weekly 1 h 23 7/16 66.5 TAU (hypertension) 22
Zeppegno et al,34 2021 RCT Clinical (breast cancer) Music therapy (group, active) + TAU 6 wk Weekly 1 h 26 No data No data TAU (radiotherapy) 29

Abbreviations: COPD, chronic obstructive pulmonary disorder; NA, not applicable; NICU, neonatal intensive care unit; RCT, randomized controlled trial; TAU, treatment as usual.