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Lidocaine relieves barrier dysfunction in H/R-induced A549 cells. (A) Cell permeability was detected using a monolayer cell paracellular permeability assay. (B) The expression levels of ZO-1, Occludin and Claudin-1 were measured via western blotting. ##P<0.01 and ###P<0.001 vs. H/R; ***P<0.001 vs. control. H/R, hypoxia/reoxygenation; ZO-1, zonula occludens-1.
