TABLE 1.
Sample | Mean ± SDb
|
||
---|---|---|---|
Cmax | Tmax | AUC0–∞, AUC0–300 | |
Serum | 2.83 ± 1.21 | 23 ± 8 | 527 ± 318, 253 ± 102 |
Diabetic ulcer | 2.18 ± 1.13 | 30 ± 11 | 278 ± 182, 209 ± 121 |
Healthy subcutis | 2.12 ± 0.55 | 23 ± 8 | 317 ± 207, 199 ± 75 |
Patients (n = 6) were given a single 200-mg dose i.v. over 20 min.
Cmax (micrograms/milliliter), maximum concentration of drug in serum; Tmax (minutes), time to maximum concentration of drug in serum; AUC0–∞ (micrograms · minute/milliliter), area under the concentration-time curve from 0 h to infinity.