Table 1.
Baseline characteristics
| Characteristic | Full analysis set (N = 44) |
|---|---|
| Male/Female, n (%) | 22 (50.0)/22 (50.0) |
| Median age (range), y | 66.5 (26-85) |
| WHO performance status (ECOG PS), n (%)* 0 1 2 | 18 (40.9) 17 (38.6) 3 (6.8) |
| Median WBC count, × 106/mL (range)† | 4.3 (0.3-115.9) |
| Median hemoglobin, g/L (range)† | 98.5 (76.0-160.0) |
| Median platelets, 106/mL (range)† | 47.5 (10.0-269.0) |
| Median neutrophils/leukocytes, % (range)† | 30.9 (1.0-78.2) |
| Median lymphocytes/leukocytes, % (range)† | 36.0 (3.0-94.5) |
| Median left ventricular ejection fraction, % (range) | 63.0 (53.0-96.0) |
| Mean liver size, cm (SD) | 8.1 (25.68) |
| Mean spleen size, cm (SD) | 7.6 (21.63) |
| Adenomegaly (longest diameter >0 cm) Laterocervical, n (%)‡ Supraclavicular, n (%)§ Axillary, n (%)§ Inguinal, n (%)§ | 4 (9.1) 1 (2.3) 2 (4.5) 1 (2.3) |
| Mediastinal mass, n (%)§ | 1 (2.3) |
| CNS disease, n (%)¶ | 6 (13.6) |
| BCR rearrangement (BM) p190, n (%) p210, n (%) p190/p210, n (%) Missing, n (%) | 29 (65.9) 9 (20.5) 2 (4.5) 4 (9.1) |
| BCR rearrangement (peripheral blood) p190, n (%) p210, n (%) p190/210, n (%) Missing, n (%) | 5 (11.4) 3 (6.8) 2 (4.5) 34 (77.3) |
| BM p190/ABL ratio × 100, median (range) | 63.4 (0-172) |
| BM p210/ABL ratio × 100, median (range) | 36.0 (0-128) |
Sum of percentages may not be 100 due to rounding.
BM, bone marrow; ECOG PS, Eastern Cooperative Oncology Group performance status; SD, standard deviation.
*
Data missing from 6 patients.
†
Evaluated in 40 patients.
‡
Data missing from 8 patients.
§
Data missing from 7 patients.
¶
Data missing from 5 patients.