Table 3.
Results from the two-way ANOVA (sex and genotype) on clinical variables in the schizophrenic group.
| Variable | rs2868370 G/A | rs2868371 C/G | rs7459185 G/C | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sex | Genotype | Sex×genotype | Sex | Genotype | Sex×genotype | Sex | Genotype | Sex×genotype | |
| Age of onset | 0.953 | 0.813 | 0.568 | 0.870 | 0.008a∗ | 0.952 | 0.149 | 0.565 | 0.033 |
| Five-factor PANSS∗∗ | |||||||||
| Positive factor | 0.659 | 0.615 | 0.394 | 0.515 | 0.429 | 0.947 | 0.027 | 0.758 | 0.095 |
| Negative factor | 0.317 | 0.441 | 0.444 | 0.367 | 0.005b∗ | 0.888 | 0.146 | 0.269 | 0.467 |
| Disorganized factor | 0.402 | 0.703 | 0.317 | 0.894 | 0.004c∗ | 0.323 | 0.528 | 0.338 | 0.412 |
| Excitement factor | 0.928 | 0.569 | 0.846 | 0.914 | 0.101 | 0.998 | 0.899 | 0.921 | 0.967 |
| Emotional factor | 0.751 | 0.679 | 0.613 | 0.418 | 0.362 | 0.606 | 0.955 | 0.163 | 0.977 |
Nominally significant p values are bolded. ∗The power of the test > 0.8. ∗∗van der Gaag's model. aMean age of onset (years): women—C/C 26.8 ± 6.8, C/G 24.3 ± 6.6, and G/G 24.9 ± 6.3; men—C/C 26.6 ± 7.3, C/G 24.5 ± 6.5, and G/G 25.5 ± 8.9. bMean negative PANSS factor scores: women—C/C 23.7 ± 5.7, C/G 22.9 ± 5.6, and G/G 27.7 ± 5.4; men—C/C 23.2 ± 5.9, C/G 22.6 ± 5.6, and G/G 26.1 ± 8.0. cMean disorganized PANSS factor scores: women—C/C 32.6 ± 6.9, C/G 30.1 ± 6.9, and G/G 35.5 ± 7.6; men—C/C 31.9 ± 6.7, C/G 31.5 ± 6.6, and G/G 35.3 ± 8.5.