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. Author manuscript; available in PMC: 2022 Jul 8.
Published in final edited form as: Adv Pharmacol. 2021 Jul 8;92:457–484. doi: 10.1016/bs.apha.2021.05.003

Figure 1. Effect of emerging chemicals on adipogenesis and adipose tissue accumulation.

Figure 1.

Emerging obesogenic chemicals are classified as food additives, ethoxylated alkylphenols, benzophenones, or chemical mixtures (top). Testing models that have been used so far for these emerging obesogens include cell-based models, such as the preadipocyte cell line 3T3-L1 and bone marrow mesenchymal stem cells (BM-MSCs) and mice. Additional in vivo studies to validate in vitro observations are needed. 3-BHA: 3-tertbutyl-4-hydroxyanisole, BP: benzophenone, BPA: bisphenol A, DOSS: dioctyl sodium sulfosuccinate, TCDD: 2,3,7,8-tetrachlorodibenzo-pdioxine, PCB: polychlorinated biphenyl, PF: perfluorinated chemicals, and UOG: unconventional oil and gas chemicals.