Table 10. Structural Group 12: Summary of Carcinogenic Potencies for Group AI Determination^26,c.

^aAs reported in LCDB unless otherwise noted; the TD₅₀ from the most sensitive organ site from the study deemed the most robust study is reported.

^bThe AI for structural group 12 was calculated based on the worst-case TD₅₀ from dinitrohomopiperazine.

^cLCDB, Lhasa Carcinogenicity Database; TD₅₀, dose producing tumors in 50% of animals.