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. Author manuscript; available in PMC: 2022 Mar 23.
Published in final edited form as: Biochem J. 2019 Dec 19;476(24):3705–3719. doi: 10.1042/BCJ20190591

Figure 5. Cuprizone selectively inhibits H2O2 release and mitochondrial oxidative stress in FaDu cells.

Figure 5.

(A) Amplex Red is measured in FaDu-NT and FaDu-shTMEM16A cells. H2O2 released is represented as % change of untreated NT (a, left panel) or % change of untreated shTMEM16A (a, right panel). (B) MitoSOX is measured in FaDu-NT and FaDu-shTMEM16A cells. MitoSOX fluorescence is shown as % change of untreated NT (b, left panel) and as % change of untreated shTMEM16A (b, right panel). Significance is shown at * P < 0.05 and ** P < 0.001 when compared with untreated control by one-way ANOVA with Dunnet’s adjustment.