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. Author manuscript; available in PMC: 2022 Mar 23.
Published in final edited form as: Biochem J. 2019 Dec 19;476(24):3705–3719. doi: 10.1042/BCJ20190591

Figure 6. Cu-chelators Cuprizone and BCS down-regulate ATP7B mRNA expression.

Figure 6.

The results of qPCR for ATP7B mRNA in OSC19 (left panel) and FaDu (right panel) after: (A) Three-hours long treatment with 20 mM NAC or 100 μM Apo treatment. Significance is calculated using unpaired t-test. (B) Six-hours long treatment with 2.5 μM Cuz. (C) Six-hours long treatment with 100 μM BCS. * P < 0.05, ** P < 0.001 and *** P < 0.0001 when compared with untreated VC or NT by one-way ANOVA with Tukey’s adjustment.