Table 2.
Linear regression analyses, statin users versus non-users n = 174
| Dependent variable | Explanatory variables | Unadjusted modelsa | Adjusted model | ||||
|---|---|---|---|---|---|---|---|
| β | B | 95% CI for B | β | B | 95% CI for B | ||
| Grip strength (kg) | Statin use | 0.17 | 2.7 | 1.0 to 4.4 | 0.07 | 1.1 | −0.5 to 2.7 |
| Age (years) | −0.20 | −0.22 | − 0.33 to − 0.11 | −0.15 | − 0.17 | −0.28 to − 0.06 | |
| Female gender | −0.74 | − 12.7 | −14.5 to − 11.0 | −0.65 | − 11.3 | − 13.0 to − 9.6 | |
| BMI (kg/m2) | 0.23 | 0.33 | 0.19 to 0.48 | 0.16 | 0.24 | 0.10 to 0.37 | |
| CIRS (0-56) | 0.31 | 0.02 | −0.18 to 0.23 | 0.04 | 0.09 | −0.10 to 0.28 | |
| FIM (18-126) | 0.20 | 0.15 | 0.08 to 0.23 | 0.20 | 0.16 | 0.08 to 0.25 | |
| CDR (0-18) | −0.11 | −0.26 | −0.51 to − 0.02 | −0.03 | − 0.07 | −0.32 to 0.18 | |
| SPPB (0-12) | Statin use | 0.06 | 0.36 | −0.56 to 1.28 | −0.02 | − 0.14 | −0.90 to 0.62 |
| Age (years) | −0.04 | −0.02 | − 0.08 to 0.05 | −0.08 | − 0.03 | −0.08 to 0.02 | |
| Female gender | −1.32 | −0.87 | −1.84 to 0.11 | −0.15 | − 0.96 | − 1.7 to − 0.16 | |
| BMI (kg/m2) | 0.17 | 0.09 | 0.01 to 0.17 | 0.10 | 0.05 | −0.01 to 0.12 | |
| CIRS (0-56) | −0.23 | −1.7 | −0.27 to − 0.06 | −0.12 | − 0.09 | −0.18 to 0.00 | |
| FIM (18-126) | 0.58 | 0.17 | 0.13 to 0.20 | 0.68 | 0.21 | 0.17 to 0.25 | |
| CDR (0-18) | 0.04 | 0.04 | −0.10 to 0.18 | 0.34 | 0.31 | 0.19 to 0.43 | |
| Gait speed (m/s) | Statin use | 0.14 | 0.06 | −0.01 to 0.12 | 0.05 | 0.02 | −0.04 to 0.08 |
| Age (years) | −0.18 | −0.005 | − 0.009 to − 0.001 | −0.14 | 0.00 | −0.01 to 0.00 | |
| Female gender | −0.12 | −0.05 | − 0.12 to 0.01 | −0.09 | − 0.04 | −0.01 to 0.02 | |
| BMI (kg/m2) | 0.06 | 0.00 | 0.00 to 0.01 | −0.04 | 0.00 | −0.01 to 0.00 | |
| CIRS (0-56) | −0.18 | −0.01 | − 0.02 to 0.00 | −0.12 | − 0.01 | −0.01 to 0.00 | |
| FIM (18-126) | 0.50 | 0.01 | 0.008 to 0.013 | 0.57 | 0.01 | 0.01 to 0.02 | |
| CDR (0-18) | −0.07 | 0.00 | − 0.01 to 0.01 | 0.22 | 0.01 | 0.01 to 0.02 | |
β is the standardized regression coefficient. B is the unstandardized regression coefficient and equals the estimated difference in the dependent variable per unit increase in the explanatory variable
aModels for grip strength are adjusted for gender (model with gender as explanatory variable not adjusted). Models for SPPB and gait speed are not adjusted
CI Confidence Interval, BMI Body mass Index, CIRS Cumulative Illness Rating Scale, FIM Functional Independence Measure, CDR Clinical Dementia Rating Scale (Sum of Boxes), SPPB Short Physical Performance Battery
Estimates in bold letters indicate a p-value below 0.05