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. 2022 Mar 23;19:21. doi: 10.1186/s12989-022-00459-w

Table 2.

Significantly increased (red) or decreased (blue) metabolite levels in rat plasma

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SiO2 nanoparticles: 1000 mg/kg body weight/day or Ag nanoparticles: 100 mg/kg body weight/day, mean values relative to vehicle controls (N = 5 per group, Welch t test; p < 0.05)

*Indicates gut microbiota-dependent metabolite