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Aripiprazole extends the lifespan of C. elegans through DOP-2. Survival curves of mutant cat-2 (A); dop-2; dop-3 (B); dop-2 (C); dop-3 (D) treated with 100 μM of aripiprazole or DMSO at 20 °C (comparison between DMSO and aripiprazole (Ari) treatment: ns = not significant with P > 0.05; ****indicated P < 0.0001, log-rank test) (see Additional file 2 for supporting data). Experiments were performed in three independent biological replicates
