Table 4.
Relative β2-AR expression (MFI: median fluorescent intensity) in peripheral blood CD4+ and CD8+ T-cell subsets before and after the 12-week intervention. MICT and HIIT did not cause any changes in the expression (MFI; median fluorescence intensity) on lymphocyte subsets and differentiated T cell subsets. [CM=central memory, EM=effector memory, EMRA=Effector Memory CD45RA+] Data are mean (SD). No significant changes were found in response to the intervention (p>0.05)
| Lymphocyte Subset | Pre (β2-AR MFI) | Post (β2-AR MFI) | p | |Hedge’s g| | ||
|---|---|---|---|---|---|---|
| CD4 β2-AR+ T cells | HIIT | 20.77 (5.22) | 23.46 (4.87) | 0.23 | 0.5 | |
| MICT | 22.31 (7.44) | 24.05 (4.98) | 0.51 | 0.26 | ||
| UC | 18.5 (6.92) | 20.27 (6.07) | 0.5 | 0.25 | ||
| β2-AR+ CD4 | β2-AR+ Naïve | HIIT | 30.11 (9.90) | 38.38 (15.33) | 0.25 | 0.61 |
| MICT | 33.54 (12.99) | 33.36 (6.73) | 0.97 | 0.02 | ||
| UC | 29.19 (18.33) | 28.99 (11.41) | 0.97 | 0.01 | ||
| β2-AR+ CM | HIIT | 22.09 (5.24) | 25.49 (6.56) | 0.12 | 0.54 | |
| MICT | 25.44 (7.95) | 26.47 (4.95) | 0.76 | 0.15 | ||
| UC | 19.31 (6.33) | 21.53 (5.27) | 0.42 | 0.36 | ||
| β2-AR+ EM | HIIT | 13.05 (2.99) | 13.79 (2.29) | 0.41 | 0.26 | |
| MICT | 13.07 (3.25) | 15.09 (3.73) | 0.14 | 0.54 | ||
| UC | 12.92 (3.67) | 13.09 (3.22) | 0.9 | 0.04 | ||
| β2-AR+ EMRA | HIIT | 17.78 (8.96) | 26.48 (14.83) | 0.24 | 0.67 | |
| MICT | 15.03 (5.12) | 25.74 (10.15) | 0.07 | 1.26 | ||
| UC | 17.02 (9.21) | 19.54 (14.54) | 0.65 | 0.19 | ||
| CD8 β2-AR+ T cells | HIIT | 28.73 (11.19) | 38.58 (21.61) | 0.19 | 0.54 | |
| MICT | 36.15 (14.17) | 39.18 (18.32) | 0.66 | 0.17 | ||
| UC | 23.87 (13.47) | 128.81 (10.94) | 0.38 | 0.38 | ||
| β2-AR+ CD8 T cells | β2-AR+ Naïve | HIIT | 28.98 (11.94) | 41.57 (27.75) | 0.23 | 0.56 |
| MICT | 34.91 (18.50) | 35.28 (22.56) | 0.96 | 0.02 | ||
| UC | 27.4 (20.74) | 30.11 (16.36) | 0.69 | 0.14 | ||
| β2-AR+ CM | HIIT | 52.62 (18.98) | 67.57 (27.14) | 0.13 | 0.6 | |
| MICT | 74.54 (33.51) | 86.42 (45.42) | 0.57 | 0.28 | ||
| UC | 43.86 (21.31) | 49.47 (22.42) | 0.5 | 0.5 | ||
| β2-AR+ EM | HIIT | 13.96 (4.2) | 17.80 (6.54) | 0.2 | 0.66 | |
| MICT | 18.11 (7.14) | 16.92 (4.78) | 0.74 | 0.19 | ||
| UC | 14.07 (2.65) | 15.76 (4.75) | 0.42 | 0.41 | ||
| β2-AR+ EMRA | HIIT | 22.71 (13.02) | 15.88 (6.1) | 0.21 | 0.63 | |
| MICT | 18.20 (11.77) | 21.75 (12.91) | 0.07 | 0.27 | ||
| UC | 16.72 (7.13) | 12.85 (5.59) | 0.27 | 0.56 | ||
| γδ T cells (Vδ2+) β2-AR+ | HIIT | 13.63 (12.05) | 17.58 (11.38) | 0.42 | 0.32 | |
| MICT | 4.67 (8.83) | 11.73 (6.4) | 0.11 | 0.87 | ||
| UC | 8.95 (8.51) | 10.45 (6.71) | 0.7 | 0.7 | ||
| NK Cells β2-AR+ | HIIT | 36.29 (11.54) | 34.89 (7.69) | 0.78 | 0.13 | |
| MICT | 33.38 (9.22) | 21.51 (6.37) | 0.51 | 0.22 | ||
| UC | 30.30 (9.23) | 30.08 (7.61) | 0.91 | 0.02 |