Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hypothesis for mechanism of increased plasma ET-1 levels in severe Covid-19 infection. Covid-19 infection may up-regulate circulating cytokines to stimulate the regulated ET-1 secretory pathway. Additionally, viral entry into endothelial cells induces cell damage and release of stored ET-1 into the circulation. (Illustration generated using Servier Medical Art (smart.servier.com) used under Creative Commons License CC BY 3.0).
