Table 2.

Differences in baseline ET-1 adjusted for confounding using univariate analyses of co-variance.

Null hypothesis: Baseline ET-1 is not significantly different:	between patient categories (controls, A, B and C)		between infected (A, B and C) and non-infected patients (controls)
Covariate Variables	Test statistic	p value after univariate adjustment	Test statistic	p value after univariate adjustment
Age	2.91	0.04	6.02	0.04
Gender	13.4	<0.001	17.1	<0.01
Ethnicity	16.0	<0.001	17.5	<0.01
HTN	7.3	<0.001	12.1	<0.01
IHD	8.9	<0.001	13.7	<0.01
DM	7.5	<0.001	12.0	<0.01
CCF	7.8	<0.001	11.9	<0.01
CKD	9.0	<0.001	13.7	<0.01

Differences in baseline ET-1 remained significant after adjustment for confounding variables. Test statistic: difference in mean square ET-1 at time 0 after adjustment for covariate variables; p value after univariate adjustment refers to probability that differences in baseline ET-1 are not significantly different between patient categories (controls, A, B and C) and between infected and non-infected patients after adjustment for differences in covariate variables.