TABLE 2.

Results for H. pylori screens (luciferase and metabolic assay) and detailed assays of analogous hit compounds Active2 and Active2a; TABLE includes MIC, minimal bactericidal concentration (MBC), and IC₅₀ results of luciferase flagellar (flaA) reporter assay for both compounds

Compound name	Luciferase screen (% of PCa)	Metabolic activity (% PCa)	MIC	MBC	IC50_luciferase
Active2	1.43	107.7	>32 μg/mL	>32 μg/mL	≤3,05 μg/mL
Active2a	2.59	102.2	>32 μg/mL	>32 μg/mL	≤2,74 μg/mL

^aPC = positive control in screen.