TABLE 7.
Impact of screening on HTLV-1 transmission through blood products
| Study | Country of research | Study design | HTLV-1 screening | Prior to implementation of donor screening (%) | Postimplementation of donor screening (%) |
|---|---|---|---|---|---|
| Kamihira et al., 1987 (442) | Japan | Before and after comparison | PA | 53.6 | 0.9 (n = 1)a |
| Nelson et al., 1992 (443) | United States | Before and after comparison | ELISA and confirmatory WB/RIPA | 0.0039 (n = 2) | 0.0 |
| Inaba et al., 1999 (444) | Japan | Prospective cohort | Second-generation PA | 0.021 (n = 1)b |
a
One seroconversion occurred due to blood being used from a different donation center that did not screen.
b
Follow-up of patient failed to confirm whether or not seroconversion was due to transfusion.