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. 2022 Feb 18;8(2):000779. doi: 10.1099/mgen.0.000779

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© 2022 The Authors

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Fig. 1. — Phylogenomic tree and pan-genome of 187 S . aureus from human and bovine origins. (a) All bovine IMI-associated S. aureus isolates except Sa1158c (CC8) were clustered into three main clades: CC151, CC126, and CC97. (b) The pan-genome of 187 S . aureus isolates were subdivided into four groups: core (genes present in 99 % ≤isolates ≤100 %), soft core (95 % ≤isolates <99 %), shell (15 % ≤isolates <95 %), and cloud genes (0 % ≤isolates <15 %). (c) The red dotted line divides the graph into two features: total pan-genome in size (top) and the number of new genomes added to the total pan-genome (bottom) as new S. aureus genomes are added. The graph indicates an open state, and new genes are likely to be discovered continually as new genomes are added to the analysis.