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. 2022 Feb 21;8(2):000676. doi: 10.1099/mgen.0.000676

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Fig. 3. — Inferred structure and differentiated amino acid sites of multidrug efflux pump related proteins. (a) TolC-AcrA-AcrB of E. coli and its H. pylori homologues. (b) HefC (MWE_0907), modelled on PDB 3W9I (MexB of Pseudomonas aeruginosa ). (iii) HefC modelled on PDB 3AOD (AcrB of E. coli). Yunnan-specific N86S is at the entrance of channel III. (c) HefD (MWE_1139), modelled on PDB 5BUN (ST50 from Salmonella enterica subsp. enterica serovar Typhi). Yellow spheres indicate Mongol-differentiated E219D.