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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Phytother Res. 2021 Oct 26;35(11):6255–6269. doi: 10.1002/ptr.7271

FIGURE 6.

FIGURE 6

Resveratrol reduces bone resorption after heat-shock induction of rankl:HSE:CFP in medaka larvae. (a) Fixed bone staining with Alizarin Red in Col10α1:mGFP/Rankl:HSE:CFP medaka larvae at 14 dpf. (b) Fixed bone staining with Alizarin Red in Col10α1:mGFP/Rankl:HSE:CFP medaka larvae at 14 dpf after RANKL induction. (c,d) Fixed bone staining with Alizarin Red in Col10α1:mGFP/Rankl:HSE: CFP medaka larvae at 14 dpf. After RANKL induction and resveratrol treatments. Normal centra and arches are observed in control group. Lesions in centra and arches are observed in the heat-shock RANKL-induced control group. Resveratrol treatments improved centra recovery and reduced bone resorption