Table 3.
ROC statistics for the DBS IgG ELISA (Toronto)
| Antigen | Spike | RBD | N | ≥ 2 Positive antigens |
|---|---|---|---|---|
| AUC | 0.99 | 0.99 | 0.99 | N/A |
| Threshold (Cut point) | 0.482 | 0.324 | 0.642 | N/A |
| FPR | 0.01 | 0.01 | 0.01 | 0.00 |
| TPR | 0.98 | 0.98 | 0.92 | 0.98 |
| Number of samples used to generate ROC curves a | ||||
|---|---|---|---|---|
| Antigen | Spike | RBD | N | ≥ 2 Positive antigens |
| Patients with COVID‐19 | 97 | 97 | 97 | 97 |
| Number excluded | 0 | 0 | 0 | 0 |
| Total analyzed | 97 | 97 | 97 | 97 |
| Pre‐COVID‐19 (negative) | 90 | 90 | 90 | 90 |
| Number excluded | 3 | 1 | 2 | 4 |
| Total analyzed | 87 | 89 | 88 | 86 |
a
NML panel 4. Each sample was analyzed in duplicate (the unique numbers of samples are shown). Replicates were treated as separate samples in the ROC analysis. Negative samples were excluded from the analysis if the replicates were > 4 SDs from the mean.