Scheme 5. Synthesis of flavone-based MAO inhibitors using click chemistry (CuAAC reaction). Reagents and conditions: (a) 1. CH3COCl, pyridine; 2. AlCl3, 130 °C; (b) 1. Ba(OH)2, EtOH; 2. I2, DMSO, 130 °C; 3. NBS, BPO, CCl4, reflux; 4. NaN3, DMF.
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