Figure 4.

Expression of glucocorticoid target genes in human hippocampal tissue. Hippocampal mRNA levels of glucocorticoid target genes assessed in dexamethasone-treated tissue and controls with β-actin normalization. Gene expression of (A) NR3C2 (MR) and NR3C1 (GR), (B) putative MR-specific targets, (C) classical, mixed GR/MR targets and (D) putative GR-specific targets in n = 1 dexamethasone-treated patient vs n = 8 controls. Two tissue samples were independently processed with each having two independent cDNA samples (illustrated as squares and diamonds).