Table 1.
Correlation Between SIRT7 Expression and Clinicopathological Characteristics in KIRC
| Characteristic | Levels | Low Expression of SIRT7 | High Expression of SIRT7 | p |
|---|---|---|---|---|
| n | 269 | 270 | ||
| T stage, n (%) | T1 | 152 (28.2%) | 126 (23.4%) | 0.030 |
| T2 | 35 (6.5%) | 36 (6.7%) | ||
| T3 | 80 (14.8%) | 99 (18.4%) | ||
| T4 | 2 (0.4%) | 9 (1.7%) | ||
| N stage, n (%) | N0 | 118 (45.9%) | 123 (47.9%) | 0.529 |
| N1 | 6 (2.3%) | 10 (3.9%) | ||
| M stage, n (%) | M0 | 234 (46.2%) | 194 (38.3%) | 0.021 |
| M1 | 31 (6.1%) | 47 (9.3%) | ||
| Pathologic stage, n (%) | Stage I | 149 (27.8%) | 123 (22.9%) | 0.068 |
| Stage II | 31 (5.8%) | 28 (5.2%) | ||
| Stage III | 55 (10.3%) | 68 (12.7%) | ||
| Stage IV | 33 (6.2%) | 49 (9.1%) | ||
| Primary therapy outcome, n (%) | PD | 5 (3.4%) | 6 (4.1%) | 0.554 |
| SD | 4 (2.7%) | 2 (1.4%) | ||
| PR | 0 (0%) | 2 (1.4%) | ||
| CR | 66 (44.9%) | 62 (42.2%) | ||
| Gender, n (%) | Female | 85 (15.8%) | 101 (18.7%) | 0.184 |
| Male | 184 (34.1%) | 169 (31.4%) | ||
| Race, n (%) | Asian | 1 (0.2%) | 7 (1.3%) | < 0.001 |
| Black or African American | 18 (3.4%) | 39 (7.3%) | ||
| White | 246 (46.2%) | 221 (41.5%) | ||
| Histologic grade, n (%) | G1 | 4 (0.8%) | 10 (1.9%) | 0.108 |
| G2 | 128 (24.1%) | 107 (20.2%) | ||
| G3 | 98 (18.5%) | 109 (20.5%) | ||
| G4 | 33 (6.2%) | 42 (7.9%) | ||
| Age, meidan (IQR) | 61 (53, 70) | 60 (51, 69) | 0.943 |