Table 3.
The Association Between KIRC Patient OS and Clinicopathological Findings Identified Through Univariate and Multivariate Cox Regression Analyses of TCGA Patients
| Characteristics | Total (N) | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|
| Hazard Ratio (95% CI) | P value | Hazard Ratio (95% CI) | P value | ||
| T stage (T2&T3&T4 vs T1) | 539 | 2.917 (2.095–4.061) | <0.001 | 0.649 (0.304–1.385) | 0.264 |
| N stage (N1 vs N0) | 257 | 3.453 (1.832–6.508) | <0.001 | 1.402 (0.693–2.833) | 0.347 |
| M stage (M1 vs M0) | 506 | 4.389 (3.212–5.999) | <0.001 | 2.449 (1.446–4.148) | <0.001 |
| SIRT7 (High vs Low) | 539 | 1.827 (1.346–2.481) | <0.001 | 2.043 (1.300–3.213) | 0.002 |
| Pathologic stage (Stage III&Stage IV vs Stage I&Stage II) | 536 | 3.946 (2.872–5.423) | <0.001 | 2.561 (1.185–5.535) | 0.017 |
| Age (>60 vs ≤60) | 539 | 1.765 (1.298–2.398) | <0.001 | 1.779 (1.156–2.738) | 0.009 |
| Histologic grade (G3&G4 vs G1&G2) | 531 | 2.702 (1.918–3.807) | <0.001 | 1.885 (1.129–3.149) | 0.015 |
| Gender (Male vs Female) | 539 | 0.930 (0.682–1.268) | 0.648 | ||
| Race (Black or African American&White vs Asian) | 532 | 1.812 (0.253–12.963) | 0.554 | ||
| Laterality (Right vs Left) | 538 | 0.706 (0.523–0.952) | 0.023 | 1.033 (0.667–1.601) | 0.884 |