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. 2022 Mar 23;8(12):eabk1410. doi: 10.1126/sciadv.abk1410

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Fig. 5. — (A) PRESTO-Tango screen of Consomatin Ro1 (10 μM) at 318 human GPCRs (x axis) identified SST₄ and SST₁ as the molecular target. Plotted values represent means ± SD of four technical replicates. (B and C) Representative concentration-response curves at the five human SS receptor subtypes comparing (B) Consomatin Ro1 or (C) Consomatin G1 with human SS-14 using the β-arrestin recruitment assay (error bars represent SD of three technical replicates), as well as bar graphs showing the respective pEC₅₀ values (error bars represent CI95 of three to seven independent repeats). RLU, relative luminescence units. Illustration credit: Paula Flórez Salcedo, University of Utah.