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. 2022 Jan 25;21(6):618–629. doi: 10.1080/15384101.2022.2030168

Figure 5.

Figure 5.

Overexpression of PTGS2 canceled out the inhibitory effect of upregulation of miR-26a-5p on the viability and proliferation of NPC cells in vitro. (a) Western blot revealed that overexpression of miR-26a-5p and PTGS2 plasmid reversed the down-regulation of PTGS2 protein induced by overexpression of miR-26a-5p in C666-1 and 5–8 F cells. (b) CCK-8 assay showed that overexpression of miR-26a-5p and PTGS2 plasmid reversed the inhibition of C666-1 and 5–8 F cell viability induced by upregulation of miR-26a-5p. (c) BrdU assay showed that overexpression of miR-26a-5p and PTGS2 plasmid reversed the inhibition of C666-1 and 5–8 F cell proliferation induced by upregulation of miR-26a-5p. The error bars indicate SD. n = 3. *P < 0.05, **P < 0.001 suggested a statistically significant difference in comparison with blank group. #P < 0.05, ##P < 0.001 suggested a statistically significant difference in comparison with OE + mimic group.