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. 2021 Apr 27;18(2):240–253. doi: 10.1080/15548627.2021.1917131

Figure 4.

Figure 4.

circRNAs affect cardiovascular diseases by regulating autophagy. In cardiovascular diseases, circ101237, circHipk2, and circPan3 promote autophagy whereas circZnf292, Acr, and circPan3 inhibit autophagy, and this ultimately leads to reduced cardiomyocyte apoptosis and a reduced myocardial necrosis area.