TABLE 1.
In vitro activities of polycationic peptides and other antimicrobial agents against R. equi
| Strain no. | MIC (μg/ml)a
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGII | NSN | RNL | AM | AZI | CLR | CRO | D | NET | OFX | RFB | RA | VA | |
| 1 | 50.8 | 1.6 | 3.2 | 4.0 | <0.1 | <0.1 | 0.3 | 0.1 | 1.0 | 1.3 | <0.1 | <0.1 | <0.1 |
| 2 | 25.4 | 1.0 | 4.0 | 6.3 | 0.1 | <0.1 | 0.1 | 0.5 | 1.6 | 1.0 | <0.1 | <0.1 | <0.1 |
| 3 | 64.0 | 16.0 | 10.1 | 8.0 | <0.1 | <0.1 | 0.2 | 0.1 | 0.5 | 2.0 | 0.1 | 0.1 | <0.1 |
| 4 | 25.4 | 5.0 | 4.0 | 5.0 | 0.1 | 0.1 | <0.1 | 0.6 | 0.4 | 0.5 | <0.1 | <0.1 | <0.1 |
| 5 | 101.6 | 10.1 | 12.7 | 16.0 | <0.1 | <0.1 | 0.8 | 1.0 | 2.0 | 2.5 | 0.1 | 0.2 | <0.1 |
| 6 | 32.0 | 5.0 | 4.0 | 10.1 | <0.1 | <0.1 | <0.1 | 0.5 | 0.1 | 0.6 | 0.1 | 0.2 | <0.1 |
a
MICs are geometric means of independent MIC determinations conducted in triplicate. Abbreviations: MGII, magainin II; NSN, nisin; RNL, ranalexin; AM, ampicillin; AZI, azithromycin; CLR, clarithromycin; CRO, ceftriaxone; D, doxycycline; NET, netilmicin; OFX, ofloxacin; RFB, rifabutin; RA, rifampin; VA, vancomycin.