Figure 4.

LC-derived Exos have high expression of circPVT1.

Notes: The expression of circPVT1 in HBE cell-derived Exos and A549 cell-derived Exos was performed by qRT-PCR (A) (n = 3). qRT-PCR was used to detect the circPVT1 level in blood-derived Exos from 60 healthy volunteers and 60 LA patients (B) (n = 60). Kaplan–Meier survival curve was employed to analyze the overall survival (C); **P < 0.01, compared to the Exo-B group and Healthy people group; *P < 0.05, compared to the Low group; LC, lung cancer; Exos, exosomes; LA, lung adenocarcinoma.