TABLE 1.
Patient | Tx organ | Age (y)/gender | BMI | Transplant indication | MELD/eGFR on day Tx | COVID-19 severity | Interval positive PCR and Tx (d) | Follow-up after Tx (d) | Post-Tximmunosuppression | Alive/functioning graft at last follow-up | Allograft rejection/reinfection |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | 67/M | 21 | ICU cholangiopathy | 20/92 | Critical: ARDS for which ICU admission with invasive ventilation, ECMO, and dialysis | 167 | 226 | <3 m: BM + Tac + MMF>3 m: Tac + MMF | Yes/yes | No/no |
2 | Liver | 68/M | 29 | NASH and HCC | 10/93 | Asymptomatic | 169 | 148 | <3 m: BM + Tac + MMF + MP>3 m: Tac + MMF | Yes/yes | No/no |
3 | Liver | 50/F | 27 | AIH and PBC | 25/116 | Critical: ARDS for which ICU admission with invasive ventilation | 195 | 156 | <3 m: BM + Tac + MMF + MP>3 m: Tac + MMF | Yes/yes | No/no |
4 | Liver | 57/F | 36 | ALD and HCC | 17/87 | Mild: anosmia and loss of taste, no hospitalization | 26 | 95 | <3 m: BM + Tac + MMF + MP>3 m: Tac + MMF | Yes/yes | No/no |
5 | Liver | 52/F | 26 | Decompensated ALD | 31/123 | Mild: cough and myalgia, no hospitalization | 60 | 65 | <3 m: BM + Tac + MMF + MP | Yes/yes | No/no |
6 | Liver + kidney | 72/F | 22 | ADPKD and ESKD | 23/9 | Asymptomatic | 56 | 233 | <3 m: BM + Tac + MMF + MP>3 m: Tac + MP | Yes/yes | No/no |
7 | Liver + kidney | 69/M | 25 | ICU cholangiopathy and kidney failure | 19/52 | Critical: ARDS for which ICU admission with invasive ventilation, ECMO, dialysis, and MARS | 148 | 38 | <3 m: BM + Tac + MMF | No/no | No/no |
8 | Liver + kidney | 63/M | 28 | NASH and hepatorenal syndrome | 45/17 | Asymptomatic | 47 | 30 | <3 m: BM + Tac + MMF + MP | Yes/yes | No/no |
9 | Kidney | 69/M | 30 | Dent’s disease | –/6 | Severe: loss of taste, anorexia, nausea, dyspnea with hospitalization, and noninvasive O2 supply | 246 | 151 | <3 m: Tac + MMF + MP>3 m: Tac + MMF + MP | Yes/yes | No/no |
10 | Kidney | 62/M | 35 | Nephroangiosclerosis | –/6 | Asymptomatic | 49 | 270 | <3 m: Tac + MMF + MP>3 m: Tac + MMF | Yes/yes | No/no |
11 | Kidney | 61/M | 30 | Hypertensive nephropathy | –/16 | Critical: ARDS for which ICU admission with invasive ventilation | 339 | 10 | <3 m: Tac + MMF + MP | Yes/yes | No/no |
ADPKD, autosomal dominant polycystic kidney disease; AIH, autoimmune hepatitis; ALD, alcohol-related liver disease; ARDS, acute respiratory distress syndrome; BM, basiliximab; BMI, body mass index; ECMO, extracorporeal membrane oxygenation; eGFR, estimated glomerular filtration rate in mL/min/1.73 m2 (Chronic Kidney Disease Epidemiology Collaboration); ESKD, end-stage kidney disease; HCC, hepatocellular carcinoma; ICU, intensive care unit; MARS, molecular adsorbent recirculating system; MELD, model of end-stage liver disease; MMF, mycophenolate mofetil; MP, methylprednisolone; NASH, nonalcoholic steatohepatitis; PBC, primary biliary cell; Tac, tacrolimus; Tx, transplantation; <3 m, within first 3 mo after Tx; >3 m, beyond 3 mo after Tx.