Table 6.

LV functional parameters in DBA/2 and D2-mdx mice at 10 and 18 weeks.

		DBA/2	D2-mdx
			Vehicle	Perindopril	Debio-025	Debio-025+Perindopril
FS (%)	10 weeks	38 ± 9.50	39.5 ± 7.4	41.3 ± 6.7	33.4 ± 7.8	38.5 ± 5.9
	18 weeks	46.8 ± 9.4	40.8 ± 6.6	37.6 ± 9.2	39.9 ± 7.2	31.4 ± 8.4
EF (%)	10 weeks	68.6 ± 12.0	70.6 ± 8.8	72.7 ± 8.4	62.6 ± 11.4	69.6 ± 7.6
	18 weeks	78.2 ± 9.0	72.1 ± 8.3	67.4 ± 11.5	71.1 ± 9.0	59.0 ± 11.9
HR (bpm)	10 weeks	415.3 ± 50.3	363.5 ± 42.2	378.3 ± 53.3	342.3 ± 41.4	315.0 ± 43.6
	18 weeks	442.8 ± 58.5∗	348.0 ± 61.7	317.8 ± 56.5	309.8 ± 27.4	341.0 ± 63.1