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Transcriptome analysis of virus-host interactions at the single-cell level. (A) ScRNA-seq reveals distinct cell subpopulations. Combined with phenotypical analysis, single-cell transcriptome analysis could be used to investigate viral diversity and identify cell subpopulations with specific phenotypes. (B-D) Characteristics of main scRNA-seq technologies (Fluidigm C1, Drop-seq and 10X) applied in the field of virology.
