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. 2022 Mar 24;23:S67–S76. doi: 10.1016/j.vacun.2022.03.002

Table 3.

Association of side effects and post-vaccination health issues with vaccines.

Health issues AZD1222® (n = 228) BBV152® (n = 30) Total P-Value
Myalgia 43 (18.85%) 9 (30%) 52 (20.15%) 0.153
Fatigue 34 (17.52%) 2(6.67%) 36 (13.95% 0.220
Sadness/Irritability 5 (2.2%) 1 (3.33%) 6 (2.31%) 0.697
Lack of concentration/Excessive worry 5 (2.2%) 3 (30%) 8 (3.1) % 0.020
Paraesthesia 3 (1.32%) 0 3 (1.16%) 0.527
Ageusia 2 (0.87%) 0 2 (0.77%) 0.481
Cough and colds Recently suffering 70 (30.70%) 9 (30%) 79 (30.6%) 0.938
Increase in frequency 33 (14.47%) 1(3.33%) 34 (13.18%) 0.090
Longer recovery time 24 (10.53%) 2 (6.67%) 26 (10.08%) 0.509
mMRC Grade 0 161(70.6%) 21(70%) 182 (70.54%) 0.97
Grade 1 53 (23.24%) 6(20%) 59 (22.86%)
Grade 2 5 (2.19%) 1 (3.33%) 6 (2.32%)
Grade 3 8 (3.51%) 2 (6.67%) 10 (3.88%)
Grade 4 1 (0.44%) 0 1 (0.39%)
EQ5D5L Mobility No problems 220(96.49%) 28 (93.33%) 248 (96.1%) 0.562
Slight problems 4 (1.75%) 2 (6.67%) 6 (2.32%)
Moderate problems 1 (0.44%) 0 1 (0.4%)
Severe problems 1 (0.44%) 0 1 (0.4%)
Extreme problems 2(0.87%) 0 2(0.77%)
Selfcare No problems 219 (96.05%) 28(93.33%) 247 (95.73%) 0.545
Slight problems 4 (1.75%) 1(3.33%) 5 (1.94%)
Moderate problems 1 (0.44%) 1(3.33%) 2(0.77%)
Severe problems 1 (0.44%) 0 1(0.4%)
Extreme problems 3(1.32%) 0 3(1.16%)
Usual activities No problems 212 (92.98%) 28 (93.33%) 240 (93.02%) 0.635
Slight problems 8 (3.51%) 2 (6.67) 10 (3.88%)
Moderate problems 4 (1.75%) 0 4 (1.55%)
Severe problems 2 (0.87%) 0 2 (0.77%)
Extreme problems 2 (0.87%) 0 2 (0.77%)
Pain/ Discomfort No problems 192 (84.21%) 25 (83.33%0 217 (84.1%) 0.473
Slight problems 28 (12.28%) 4(13.33%) 32(12.4%)
Moderate problems 1(0.44%) 1(3.33%) 2 (0.77%)
Severe problems 6 (2.63%) 0 6 (2.32%)
Extreme problems 1(0.4%) 0 1 (0.4%)
Anxiety/Depression No problems 192(84.21%) 26 (86.67%) 218 (84.5%) 0.386
Slight problems 21 (9.2%) 4 (13.33%) 25 (9.68%)
Moderate problems 9(3.95%) 0 9 (3.5%)
Severe problems 4 (1.75%) 0 4(1.55%)
Extreme problems 2(0.87%) 0 2(0.77%)
Duration from last jab of vaccination 30–90 days 46 (17.82%) 0.941
91–180 days 30 (11.6%)
More than 180 days 17 (6.58%)
Side effect of vaccine Injection site pain 126 (55.26%) 9(30%) 135 (52.33%) 0.009⁎⁎
Chills 34 (17.52%) 0 34 (13.2%) 0.023*
Headache 48 (21.1%) 8(26.67%) 56 (21.7%) 0.483
Myalgia 86 (37.7%) 10(33.33%) 96 (37.2%) 0.640
Fever 4 (1.75%) 0 4 (1.55%) 0.318
Weakness 2 (0.87%) 0 2 (0.77%) 0.481
Fainting sensation 3 (1.32%) 0 3 (1.16%) 0.388
Nausea 6 (2.63%) 0 6 (2.32%) 0.369
Total 171 (75%) 20 (66.67%) 191 (74.03%) 0.328
Leave taken from daily work 76 (33.33%) 3(10%) 79 (30.62%) 0.009⁎⁎

Significant levels 0.05 are shown in bold.