Table 5.
Risk factors associated with hematologic toxicities
| Grade 4 ALC | Grade 3 to 4 Hg | |||
|---|---|---|---|---|
|
|
|
|||
| OR | P-value | OR | P-value | |
| Age | 1.018 | 0.318 | 1.019 | 0.533 |
|
| ||||
| Ethnicity | ||||
|
| ||||
| Non-hispanic | 1 | Ref | - | - |
|
| ||||
| Hispanic | 1.031 | 0.941 | - | - |
|
| ||||
| BMI | 0.928 | 0.025 | 0.922 | 0.168 |
|
| ||||
| HIV diagnosis | 2.3 | 0.291 | 1.65 | 0.658 |
|
| ||||
| Diabetes diagnosis | 0.49 | 0.3 | 0.49 | 0.999 |
|
| ||||
| Histology | ||||
|
| ||||
| Other | 1 | Ref | 1 | Ref |
|
| ||||
| SCC | 3.872 | 0.04 | 2.088 | 0.495 |
|
| ||||
| Stage | ||||
|
| ||||
| I | 1 | Ref | - | - |
|
| ||||
| II | 2.04 | 0.128 | - | - |
|
| ||||
| III | 5.564 | 0.001 | - | - |
|
| ||||
| Post-operative | 0.855 | 0.772 | - | - |
|
| ||||
| Length of XRT (days) | 1.004 | 0.663 | 1.005 | 0.685 |
|
| ||||
| Use of Extended fields | 2.055 | 0.064 | 1.279 | 0.699 |
|
| ||||
| Baseline ALC | 0.338 | 0.001 | - | - |
|
| ||||
| Baseline Hg | - | - | 0.286 | <0.001 |
ALC, absolute lymphocyte count; Hg, hemoglobin; OR, overall risk; BMI, body mass index; HIV, human immunodeficiency virus; Ref, reference; XRT, radiotherapy.