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CGRP receptor antagonists attenuate CGRP action in vivo. Effects of (A) αCGRP8-37, (B) olcegepant, (C) V8C-palmitate and (D) K24C-palmitate on CIDV in male (left) and female (right) mice. Inset graphs show corresponding AUC mean values over the 15 min measurement timeframe following capsaicin application to the ear. ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001. Each treatment group comprises four to five mice with corresponding saline controls.
