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Comparison between αCGRP8-37 and V8C-palmitate for antagonism onset of CGRP action in vivo. αCGRP8-37 (960 nmol/kg) and V8C-palmitate (960 nmol/kg) were administered at 0 min (A,F), 10 min (B,G), 20 min (C,H), 30 min (D,I) and 60 min (E,J) prior to anesthesia and capsaicin application. ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001. Each treatment group comprised six mice with corresponding saline controls.
