Table 1.
Ref | Publication date | Age (years) | Sex | Country | Comorbidities | COVID-19 Sx | Severity of COVID-19 | COVID-19 therapy | Steroids | Hospital admission | ICU admission | Mech. vent | Timing of Crypto Dg (D)a |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
[9] | 8/2021 | 75 | M | USA | HTN, DM, OA, obesity | Fever, SOB | Severe | Remdesivir | Yes | Yes | Yes | Yes | Postmortem |
[10] | 8/2021 | 55 | M | Germany | A-fib, dilated cardiomyopathy | SOB | Severe | N/A | Yes | Yes | Yes | Yes | D13 |
[11] | 6/2021 | 73 | F | USA | None | Fever, SOB | Severe | N/A | Yes | Yes | Yes | Yes | D17 |
[12] | 12/2020 | 60 | M | Qatar | HTN, DM, IHD | SOB | Severe | Tocilizumab | Yes | Yes | Yes | Yes | D48 |
[13] | 12/2020 | 24 | M | USA | HIV | SOB, fatigue, HA | Mild | N/A | No | Yes | Yes | No | D5 |
[14] | 10/2020 | 75 | M | Brazil | HTN, kidney transplant, liver cirrhosis | Cough, SOB | Severe | N/A | Yes | Yes | Yes | Yes | Postmortem |
[15] | 1/2021 | 78 | M | USA | HTN, COPD | Fever, SOB, HA | Severe | Remdesivir | Yes | Yes | Yes | Yes | D22 |
[16] | 4/2021 | 76 | F | USA | HTN | Diarrhea, weakness, confusion | Severe | Remdesivir, tocilizumab | Yes | Yes | Yes | Yes | D49 |
[17] | 12/2021 | 78 | M | Spain | HTN, DM, CKD | Fever, SOB, asthenia | Severe | N/A | Yes | Yes | Yes | Yes | D75 |
[18] | 3/2022 | 59 | M | USA | COPD, DM, liver cirrhosis | SOB | Severe | N/A | Yes | Yes | Yes | Yes | D33 |
[19] | 5/2021 | 76 | F | USA | HTN, osteoarthritis | Diarrhea, weakness, confusion | Severe | Remdesivir, tocilizumab | Yes | Yes | Yes | Yes | D44 |
[20] | 01/2022 | 57 | M | USA | HTN | Fever, SOB | Severe | Remdesivir | Yes | Yes | Yes | Yes | D36 |
[21] | 11/2021 | 59 | M | USA | HTN, DM, obesity | Fever, SOB | Severe | Remdesivir | Yes | Yes | Yes | Yes | D10 |
A-fib atrial fibrillation, COPD chronic obstructive pulmonary disease, Crypto cryptococcosis, Dg diagnosis, F female, HIV human immunodeficiency virus, IHD ischemic heart disease, HTN hypertension, D (days), DM diabetes mellitus, HA headache, M male, Mech. vent. mechanical ventilation, OA osteoarthritis, Sx symptoms, SOB shortness of breath, Ref reference
aTiming of cryptococcosis diagnosis from the time of COVID-19 diagnosis