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. 2022 Feb 1;603(7902):700–705. doi: 10.1038/s41586-022-04462-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — All four lobes of the right lung of infected hamsters (n = 3 for each virus) at 3 d.p.i. were immunohistochemically stained with anti-SARS-CoV-2 N monoclonal antibody. The circumference of all bronchioles (less than 500 µm diameter) is delineated in blue, and the positivity of N protein in bronchiole is indicated by magenta. Each length is indicated in the lower left of the panel by each colour. The number in parenthesis indicates the percentage of the N-positive bronchioles in the circumference of all bronchioles. The summarized result is shown in the right panel of Fig. 4d.