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. 2022 Mar 9;603(7902):721–727. doi: 10.1038/s41586-022-04499-2

Extended Data Fig. 7. T cell reactivity against two substitutant peptides.

Extended Data Fig. 7

Flow cytometric analysis of CD8+ T cells following co-culture of naive CD8+ T cells and autologous monocyte-derived dendritic cells pulsed with peptide or DMSO vehicle. Plots show T cells reactive to SA-phycoerythrin (PE) and SA-phycoerythrin-CF594 (PE-CF594)-labelled pMHC multimers complexed with the KLH4L substitutant peptide YFDPHTNKF (Wells #1 and 3), or reactive to SA-PE and SA-allophycocyanin (SA-APC)-labelled pMHC multimers complexed with the BI1 (TMBIM6) substitutant peptide EHGDQDYIF (Well #2).