Table 1.
Summary of main characteristics for all participants
All participants (n=15 666) | ||
---|---|---|
Clinical setting | ||
Outpatient | 15 541 (99·2%) | |
Other setting* | 125 (0·8%) | |
Age, years | 34 (28–42) | |
Sex | ||
Female | 10 388 (66·3%) | |
Male | 5278 (33·7%) | |
ART status | ||
On ART | 4347/15 663 (27·8%) | |
Outpatients on ART | 4328/15 538 (27·9%) | |
Not on ART | 11 316/15 663 (72·2%) | |
Outpatients not on ART | 11 210/15 538 (72·1%) | |
CD4 count, cells per μL | ||
n | 15 281 | |
Median | 269 (142–439) | |
History of tuberculosis | 1955/11 148 (17·5%) | |
W4SS | 8028/15 652 (51·3%) | |
Cough | 4629/15 623 (29·6%) | |
Fever | 3391/15 631 (21·7%) | |
Weight loss | 5575/15 602 (35·7%) | |
Night sweats | 3270/15 630 (20·9%) | |
Cough lasting ≥2 weeks | 2205/10 919 (20·2%) | |
Lymphadenopathy | 374/2394 (15·6%) | |
Chest x-ray | ||
Suggestive of tuberculosis | 1296/6177 (21·0%) | |
Any abnormality | 2158/6222 (34·7%) | |
Xpert positive† | 616/8625 (7·1%) | |
Body-mass index, kg/m2 | ||
n | 12 704 | |
Median | 22 (19–26) | |
C-reactive protein, mg/L‡ | ||
n | 3582 | |
Median | 4 (2–21) | |
≥10 mg/L | 1259 (35·1%) | |
Haemoglobin, g/dL | ||
n | 5118 | |
Median | 12 (10–13) | |
<10 g/dL | 1093 (21·4%) |
Data are median (IQR), n (%), or n/N (%). If data were not available for the full cohort, the revised denominator or count is provided. ART=antiretroviral therapy. W4SS=WHO four-symptom screening.
One study was among people living in prison.
Sputum or non-sputum sample Xpert result, or both.
Measured with a point-of-care assay (n=2695) or laboratory assay (n=887).