Table 1:
Demographic characteristics of cavernous angioma lesions with versus without bleed/growth within a year after imaging.
| Demographics | Lesional bleed/growth (N=23) | No bleed/growth (N=722) | p-value |
|---|---|---|---|
| Age, N (%) | 0.34† | ||
| < 30 years old | 13 (56.5%) | 312 (43.2%) | |
| 30 – 50 years old | 7 (30.4%) | 233 (32.3%) | |
| > 50 years old | 3 (13.0%) | 177 (24.5%) | |
| Female, N (%) | 17 (73.9%) | 508 (70.4%) | 0.82 |
| Ethnicity/race, N (%) * | 0.86† | ||
| African American | 1 (4.3%) | 24 (3.3%) | |
| Ashkenazi Jewish | 0 (0.0%) | 7 (1.0%) | |
| Asian | 0 (0.0%) | 8 (1.1%) | |
| Hispanic of Mexican descent | 0 (0.0%) | 8 (1.1%) | |
| Hispanic of other descent | 0 (0.0%) | 34 (4.7%) | |
| White/Caucasian | 22 (95.7%) | 627 (87.1%) | |
| Other | 0 (0.0%) | 12 (1.7%) | |
| Sporadic, N (%) | 8 (34.8%) | 143 (19.8%) | 0.11 |
| Familial genotype, N (%) | 0.92† | ||
| CCM1 | 4 (26.7%) | 115 (19.9%) | |
| CCM2 | 0 (0.0%) | 29 (5.0%) | |
| CCM3 | 10 (66.7%) | 394 (68.0%) | |
| Multifocal unknown | 1 (6.7%) | 41 (7.1%) | |
| Brainstem lesion, N (%) | 6 (26.1%) | 62 (8.6%) | 0.013 |
| Prior symptomatic hemorrhage, N (%) | 3 (13.0%) | 83 (11.5%) | 0.74 |
*
One patient declined to provide information on their ethnicity/race.
†
The p-values for age, ethnicity/race, and familial genotype refer to overall comparisons and not individual differences among subgroups.